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MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy

MX2 is an interferon inducible gene that is mostly known for its antiviral activity. We have previously demonstrated that MX2 is also associated with the tumorigenesis process in melanoma. However, it remains unknown which molecular mechanisms are regulated by MX2 in response to interferon signaling...

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Detalles Bibliográficos
Autores principales: Juraleviciute, Marina, Nsengimana, Jérémie, Newton‐Bishop, Julia, Hendriks, Gert J., Slipicevic, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026919/
https://www.ncbi.nlm.nih.gov/pubmed/33734579
http://dx.doi.org/10.1002/cam4.3846