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Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy

The protein disulphide isomerase (PDI) gene family is a large, diverse group of enzymes recognised for their roles in disulphide bond formation within the endoplasmic reticulum (ER). PDI therefore plays an important role in ER proteostasis, however, it also shows involvement in ER stress, a characte...

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Detalles Bibliográficos
Autores principales: Powell, Lauren E., Foster, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026947/
https://www.ncbi.nlm.nih.gov/pubmed/33742523
http://dx.doi.org/10.1002/cam4.3836