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HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice

Cone photoreceptor cell death in inherited retinal diseases, such as Retinitis Pigmentosa (RP), leads to the loss of high acuity and color vision and, ultimately to blindness. In RP, a vast number of mutations perturb the structure and function of rod photoreceptors, while cones remain initially una...

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Detalles Bibliográficos
Autores principales: Samardzija, Marijana, Corna, Andrea, Gomez-Sintes, Raquel, Jarboui, Mohamed Ali, Armento, Angela, Roger, Jerome E., Petridou, Eleni, Haq, Wadood, Paquet-Durand, Francois, Zrenner, Eberhart, de la Villa, Pedro, Zeck, Günther, Grimm, Christian, Boya, Patricia, Ueffing, Marius, Trifunović, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026998/
https://www.ncbi.nlm.nih.gov/pubmed/33159184
http://dx.doi.org/10.1038/s41418-020-00653-3