Cargando…
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice
Cone photoreceptor cell death in inherited retinal diseases, such as Retinitis Pigmentosa (RP), leads to the loss of high acuity and color vision and, ultimately to blindness. In RP, a vast number of mutations perturb the structure and function of rod photoreceptors, while cones remain initially una...
Autores principales: | Samardzija, Marijana, Corna, Andrea, Gomez-Sintes, Raquel, Jarboui, Mohamed Ali, Armento, Angela, Roger, Jerome E., Petridou, Eleni, Haq, Wadood, Paquet-Durand, Francois, Zrenner, Eberhart, de la Villa, Pedro, Zeck, Günther, Grimm, Christian, Boya, Patricia, Ueffing, Marius, Trifunović, Dragana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026998/ https://www.ncbi.nlm.nih.gov/pubmed/33159184 http://dx.doi.org/10.1038/s41418-020-00653-3 |
Ejemplares similares
-
Using Micro-Electrode-Array Recordings and Retinal Disease Models to Elucidate Visual Functions: Simultaneous Recording of Local Electroretinograms and Ganglion Cell Action Potentials Reveals the Origin of Retinal Oscillatory Potentials
por: Haq, Wadood, et al.
Publicado: (2023) -
Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones
por: Karademir, Duygu, et al.
Publicado: (2022) -
Increased H3K27 trimethylation contributes to cone survival in a mouse model of cone dystrophy
por: Miller, Annie L., et al.
Publicado: (2022) -
Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations
por: Jiao, K, et al.
Publicado: (2016) -
Electrical activation of degenerated photoreceptors in blind mouse retina elicited network-mediated responses in different types of ganglion cells
por: Haq, Wadood, et al.
Publicado: (2018)