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Regulation of dopamine-dependent transcription and cocaine action by Gadd45b

Exposure to drugs of abuse produces robust transcriptional and epigenetic reorganization within brain reward circuits that outlives the direct effects of the drug and may contribute to addiction. DNA methylation is a covalent epigenetic modification that is altered following stimulant exposure and i...

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Detalles Bibliográficos
Autores principales: Zipperly, Morgan E., Sultan, Faraz A., Graham, Guan-En, Brane, Andrew C., Simpkins, Natalie A., Carullo, Nancy V. N., Ianov, Lara, Day, Jeremy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027017/
https://www.ncbi.nlm.nih.gov/pubmed/32927466
http://dx.doi.org/10.1038/s41386-020-00828-z