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Regulation of dopamine-dependent transcription and cocaine action by Gadd45b
Exposure to drugs of abuse produces robust transcriptional and epigenetic reorganization within brain reward circuits that outlives the direct effects of the drug and may contribute to addiction. DNA methylation is a covalent epigenetic modification that is altered following stimulant exposure and i...
Autores principales: | Zipperly, Morgan E., Sultan, Faraz A., Graham, Guan-En, Brane, Andrew C., Simpkins, Natalie A., Carullo, Nancy V. N., Ianov, Lara, Day, Jeremy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027017/ https://www.ncbi.nlm.nih.gov/pubmed/32927466 http://dx.doi.org/10.1038/s41386-020-00828-z |
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