Understanding the influence of lipid bilayers and ligand molecules in determining the conformational dynamics of somatostatin receptor 2

Somatostatin receptor 2 (SSTR2) is a G-protein coupled receptor (GPCR) that controls numerous cellular processes including cell-to-cell signaling. In this study, we report how the lipid and ligand molecules influence the conformational dynamics of the membrane-bound SSTR2. Molecular simulations of d...

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Detalles Bibliográficos
Autores principales: Nagarajan, Santhosh Kumar, Babu, Sathya, Kulkarni, Seema A., Vadivelu, Aanand, Devaraju, Panneer, Sohn, Honglae, Madhavan, Thirumurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027056/
https://www.ncbi.nlm.nih.gov/pubmed/33828200
http://dx.doi.org/10.1038/s41598-021-87422-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027056/
https://www.ncbi.nlm.nih.gov/pubmed/33828200
http://dx.doi.org/10.1038/s41598-021-87422-5

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