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Understanding the influence of lipid bilayers and ligand molecules in determining the conformational dynamics of somatostatin receptor 2
Somatostatin receptor 2 (SSTR2) is a G-protein coupled receptor (GPCR) that controls numerous cellular processes including cell-to-cell signaling. In this study, we report how the lipid and ligand molecules influence the conformational dynamics of the membrane-bound SSTR2. Molecular simulations of d...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027056/ https://www.ncbi.nlm.nih.gov/pubmed/33828200 http://dx.doi.org/10.1038/s41598-021-87422-5 |