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Molecular Basis of Class B GPCR Selectivity for the Neuropeptides PACAP and VIP

The related neuropeptides PACAP and VIP, and their shared PAC1, VPAC1 and VPAC2 receptors, regulate a large array of physiological activities in the central and peripheral nervous systems. However, the lack of comparative and molecular mechanistic investigations hinder further understanding of their...

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Detalles Bibliográficos
Autores principales: Liao, Chenyi, Remington, Jacob M., May, Victor, Li, Jianing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027070/
https://www.ncbi.nlm.nih.gov/pubmed/33842547
http://dx.doi.org/10.3389/fmolb.2021.644644