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Agonal Factors Distort Gene-Expression Patterns in Human Postmortem Brains
Agonal factors, the conditions that occur just prior to death, can impact the molecular quality of postmortem brains, influencing gene expression results. Our study used gene expression data of 262 samples from ROSMAP with the detailed terminal state recorded for each donor, such as fever, infection...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027124/ https://www.ncbi.nlm.nih.gov/pubmed/33841074 http://dx.doi.org/10.3389/fnins.2021.614142 |