Agonal Factors Distort Gene-Expression Patterns in Human Postmortem Brains

Agonal factors, the conditions that occur just prior to death, can impact the molecular quality of postmortem brains, influencing gene expression results. Our study used gene expression data of 262 samples from ROSMAP with the detailed terminal state recorded for each donor, such as fever, infection...

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Detalles Bibliográficos
Autores principales: Dai, Jiacheng, Chen, Yu, Dai, Rujia, Jiang, Yi, Tian, Jianghua, Liu, Sihan, Xu, Meng, Li, Miao, Zhou, Jiaqi, Liu, Chunyu, Chen, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027124/
https://www.ncbi.nlm.nih.gov/pubmed/33841074
http://dx.doi.org/10.3389/fnins.2021.614142

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