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Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease

BACKGROUND: Dermatomyositis (DM) associated rapidly progressive interstitial lung disease (RP-ILD) has high mortality rate and poor prognosis. Galectin-9 (Gal-9) plays multiple functions in immune regulation. We investigated Gal-9 expression in DM patients and its association with DM-ILD. METHODS: A...

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Detalles Bibliográficos
Autores principales: Liang, Lin, Zhang, Ya-Mei, Shen, Ya-Wen, Song, Ai-Ping, Li, Wen-Li, Ye, Li-Fang, Lu, Xin, Wang, Guo-Chun, Peng, Qing-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027128/
https://www.ncbi.nlm.nih.gov/pubmed/33842457
http://dx.doi.org/10.3389/fcell.2021.628128