Epigallocathechin-O-3-Gallate Inhibits Trypanothione Reductase of Leishmania infantum, Causing Alterations in Redox Balance and Leading to Parasite Death

Leishmania infantum is a protozoan parasite that causes a vector borne infectious disease in humans known as visceral leishmaniasis (VL). This pathology, also caused by L. donovani, presently impacts the health of 500,000 people worldwide, and is treated with outdated anti-parasitic drugs that suffe...

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Detalles Bibliográficos
Autores principales: Inacio, Job D. F., Fonseca, Myslene S., Limaverde-Sousa, Gabriel, Tomas, Ana M., Castro, Helena, Almeida-Amaral, Elmo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027256/
https://www.ncbi.nlm.nih.gov/pubmed/33842389
http://dx.doi.org/10.3389/fcimb.2021.640561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027256/
https://www.ncbi.nlm.nih.gov/pubmed/33842389
http://dx.doi.org/10.3389/fcimb.2021.640561

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