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Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model

Skeletal muscle is responsible for the majority of glucose disposal following meals, and this is achieved by insulin-mediated trafficking of glucose transporter type 4 (GLUT4) to the cell membrane. The eight-protein exocyst trafficking complex facilitates targeted docking of membrane-bound vesicles,...

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Detalles Bibliográficos
Autores principales: Fujimoto, Brent A., Young, Madison, Nakamura, Nicole, Ha, Herena, Carter, Lamar, Pitts, Matthew W., Torres, Daniel, Noh, Hye-Lim, Suk, Sujin, Kim, Jason K., Polgar, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027262/
https://www.ncbi.nlm.nih.gov/pubmed/33647317
http://dx.doi.org/10.1016/j.jbc.2021.100482