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Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model
Skeletal muscle is responsible for the majority of glucose disposal following meals, and this is achieved by insulin-mediated trafficking of glucose transporter type 4 (GLUT4) to the cell membrane. The eight-protein exocyst trafficking complex facilitates targeted docking of membrane-bound vesicles,...
Autores principales: | Fujimoto, Brent A., Young, Madison, Nakamura, Nicole, Ha, Herena, Carter, Lamar, Pitts, Matthew W., Torres, Daniel, Noh, Hye-Lim, Suk, Sujin, Kim, Jason K., Polgar, Noemi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027262/ https://www.ncbi.nlm.nih.gov/pubmed/33647317 http://dx.doi.org/10.1016/j.jbc.2021.100482 |
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