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Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice

Hepatic glycogen metabolism is impaired in diabetes. We previously demonstrated that strategies to increase liver glycogen content in a high-fat-diet mouse model of obesity and insulin resistance led to a reduction in food intake and ameliorated obesity and glucose tolerance. These effects were acco...

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Detalles Bibliográficos
Autores principales: López-Soldado, Iliana, Guinovart, Joan J., Duran, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027280/
https://www.ncbi.nlm.nih.gov/pubmed/33667544
http://dx.doi.org/10.1016/j.jbc.2021.100498