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Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice
Hepatic glycogen metabolism is impaired in diabetes. We previously demonstrated that strategies to increase liver glycogen content in a high-fat-diet mouse model of obesity and insulin resistance led to a reduction in food intake and ameliorated obesity and glucose tolerance. These effects were acco...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027280/ https://www.ncbi.nlm.nih.gov/pubmed/33667544 http://dx.doi.org/10.1016/j.jbc.2021.100498 |