Fangchinoline suppresses conjunctival melanoma by directly binding FUBP2 and inhibiting the homologous recombination pathway

Conjunctival melanoma (CM) is a rare and fatal ocular tumour with poor prognosis. There is an urgent need of effective therapeutic drugs against CM. Here, we reported the discovery of a novel potential therapeutic target for CM. Through phenotypic screening of our in-house library, fangchinoline was...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Keting, Li, Yongyun, Wei, Jinlian, Li, Ruoxi, Yang, Jie, Shi, Jiahao, Li, Baoli, Zhu, Jin, Mao, Fei, Jia, Renbing, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027391/
https://www.ncbi.nlm.nih.gov/pubmed/33828201
http://dx.doi.org/10.1038/s41419-021-03653-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027391/
https://www.ncbi.nlm.nih.gov/pubmed/33828201
http://dx.doi.org/10.1038/s41419-021-03653-4

Ejemplares similares