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Deubiquitinase Ubp3 enhances the proteasomal degradation of key enzymes in sterol homeostasis

Sterol homeostasis is tightly controlled by molecules that are highly conserved from yeast to humans, the dysregulation of which plays critical roles in the development of antifungal resistance and various cardiovascular diseases. Previous studies have shown that sterol homeostasis is regulated by t...

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Detalles Bibliográficos
Autores principales: Lan, Qiuyan, Li, Yanchang, Wang, Fuqiang, Li, Zhaodi, Gao, Yuan, Lu, Hui, Wang, Yihao, Zhao, Zhenwen, Deng, Zixin, He, Fuchu, Wu, Junzhu, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027567/
https://www.ncbi.nlm.nih.gov/pubmed/33524398
http://dx.doi.org/10.1016/j.jbc.2021.100348