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Cryo-EM structure of the human histamine H(1) receptor/G(q) complex

Histamine receptors play important roles in various pathophysiological conditions and are effective targets for anti-allergy treatment, however the mechanism of receptor activation remain elusive. Here, we present the cryo-electron microscopy (cryo-EM) structure of the human H(1)R in complex with a...

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Detalles Bibliográficos
Autores principales: Xia, Ruixue, Wang, Na, Xu, Zhenmei, Lu, Yang, Song, Jing, Zhang, Anqi, Guo, Changyou, He, Yuanzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027608/
https://www.ncbi.nlm.nih.gov/pubmed/33828102
http://dx.doi.org/10.1038/s41467-021-22427-2