Phage gene expression and host responses lead to infection-dependent costs of CRISPR immunity

CRISPR-Cas immune systems are widespread in bacteria and archaea, but not ubiquitous. Previous work has demonstrated that CRISPR immunity is associated with an infection-induced fitness cost, which may help explain the patchy distribution observed. However, the mechanistic basis of this cost has rem...

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Detalles Bibliográficos
Autores principales: Meaden, Sean, Capria, Loris, Alseth, Ellinor, Gandon, Sylvain, Biswas, Ambarish, Lenzi, Luca, van Houte, Stineke, Westra, Edze R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027618/
https://www.ncbi.nlm.nih.gov/pubmed/33011743
http://dx.doi.org/10.1038/s41396-020-00794-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027618/
https://www.ncbi.nlm.nih.gov/pubmed/33011743
http://dx.doi.org/10.1038/s41396-020-00794-w

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