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Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

How the innate and adaptive host immune system miscommunicate to worsen COVID-19 immunopathology has not been fully elucidated. Here, we perform single-cell deep-immune profiling of bronchoalveolar lavage (BAL) samples from 5 patients with mild and 26 with critical COVID-19 in comparison to BALs fro...

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Detalles Bibliográficos
Autores principales: Wauters, Els, Van Mol, Pierre, Garg, Abhishek Dinkarnath, Jansen, Sander, Van Herck, Yannick, Vanderbeke, Lore, Bassez, Ayse, Boeckx, Bram, Malengier-Devlies, Bert, Timmerman, Anna, Van Brussel, Thomas, Van Buyten, Tina, Schepers, Rogier, Heylen, Elisabeth, Dauwe, Dieter, Dooms, Christophe, Gunst, Jan, Hermans, Greet, Meersseman, Philippe, Testelmans, Dries, Yserbyt, Jonas, Tejpar, Sabine, De Wever, Walter, Matthys, Patrick, Neyts, Johan, Wauters, Joost, Qian, Junbin, Lambrechts, Diether
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027624/
https://www.ncbi.nlm.nih.gov/pubmed/33473155
http://dx.doi.org/10.1038/s41422-020-00455-9