Intracellular trafficking of Notch orchestrates temporal dynamics of Notch activity in the fly brain

While Delta non-autonomously activates Notch in neighboring cells, it autonomously inactivates Notch through cis-inhibition, the molecular mechanism and biological roles of which remain elusive. The wave of differentiation in the Drosophila brain, the ‘proneural wave’, is an excellent model for stud...

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Detalles Bibliográficos
Autores principales: Wang, Miaoxing, Han, Xujun, Liu, Chuyan, Takayama, Rie, Yasugi, Tetsuo, Ei, Shin-Ichiro, Nagayama, Masaharu, Tanaka, Yoshitaro, Sato, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027629/
https://www.ncbi.nlm.nih.gov/pubmed/33828096
http://dx.doi.org/10.1038/s41467-021-22442-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027629/
https://www.ncbi.nlm.nih.gov/pubmed/33828096
http://dx.doi.org/10.1038/s41467-021-22442-3

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