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Intracellular trafficking of Notch orchestrates temporal dynamics of Notch activity in the fly brain
While Delta non-autonomously activates Notch in neighboring cells, it autonomously inactivates Notch through cis-inhibition, the molecular mechanism and biological roles of which remain elusive. The wave of differentiation in the Drosophila brain, the ‘proneural wave’, is an excellent model for stud...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027629/ https://www.ncbi.nlm.nih.gov/pubmed/33828096 http://dx.doi.org/10.1038/s41467-021-22442-3 |