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Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation

Macrophages acquire anti-inflammatory and proresolving functions to facilitate resolution of inflammation and promote tissue repair. While alternatively activated macrophages (AAMs), also referred to as M2 macrophages, polarized by type 2 (Th2) cytokines IL-4 or IL-13 contribute to the suppression o...

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Detalles Bibliográficos
Autores principales: Snodgrass, Ryan G., Benatzy, Yvonne, Schmid, Tobias, Namgaladze, Dmitry, Mainka, Malwina, Schebb, Nils Helge, Lütjohann, Dieter, Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027700/
https://www.ncbi.nlm.nih.gov/pubmed/33177619
http://dx.doi.org/10.1038/s41418-020-00652-4