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Diclofenac impairs the proliferation and glucose metabolism of triple-negative breast cancer cells by targeting the c-Myc pathway

Triple-negative breast cancer (TNBC) cells obtain energy mainly through aerobic glycolysis, and their glycolytic rate is significantly higher compared with that of non-TNBC cells. Glucose transporter 1 (GLUT1) is a transmembrane transporter necessary for the entry of glucose into tumor cells, hexoki...

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Detalles Bibliográficos
Autores principales: Yang, Lihui, Li, Jiachen, Li, Yongzhuo, Zhou, Yongli, Wang, Ziqian, Zhang, Dahao, Liu, Jinlu, Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027724/
https://www.ncbi.nlm.nih.gov/pubmed/33850556
http://dx.doi.org/10.3892/etm.2021.10016