Metformin prevents PFKFB3-related aerobic glycolysis from enhancing collagen synthesis in lung fibroblasts by regulating AMPK/mTOR pathway

Aerobic glycolysis has been shown to contribute to the abnormal activation of lung fibroblasts with excessive collagen deposition in lipopolysaccharide (LPS)-induced pulmonary fibrosis. Targeting aerobic glycolysis in lung fibroblasts might therefore be considered as a promising therapeutic approach...

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Detalles Bibliográficos
Autores principales: Tang, Ci-Jun, Xu, Ji, Ye, Hai-Yan, Wang, Xue-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027738/
https://www.ncbi.nlm.nih.gov/pubmed/33850553
http://dx.doi.org/10.3892/etm.2021.10013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027738/
https://www.ncbi.nlm.nih.gov/pubmed/33850553
http://dx.doi.org/10.3892/etm.2021.10013

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