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A randomized cross-over trial to define neurophysiological correlates of AV-101 N-methyl-d-aspartate receptor blockade in healthy veterans

The kynurenine pathway (KP) is a strategic metabolic system that combines regulation of neuronal excitability via glutamate receptor function and neuroinflammation via other KP metabolites. This pathway has great promise in treatment of depression and suicidality. The KP modulator AV-101 (4-chloroky...

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Detalles Bibliográficos
Autores principales: Murphy, Nicholas, Ramakrishnan, Nithya, Vo-Le, Bylinda, Vo-Le, Brittany, Smith, Mark A., Iqbal, Tabish, Swann, Alan C., Mathew, Sanjay J., Lijffijt, Marijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027791/
https://www.ncbi.nlm.nih.gov/pubmed/33318635
http://dx.doi.org/10.1038/s41386-020-00917-z