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A randomized cross-over trial to define neurophysiological correlates of AV-101 N-methyl-d-aspartate receptor blockade in healthy veterans
The kynurenine pathway (KP) is a strategic metabolic system that combines regulation of neuronal excitability via glutamate receptor function and neuroinflammation via other KP metabolites. This pathway has great promise in treatment of depression and suicidality. The KP modulator AV-101 (4-chloroky...
Autores principales: | Murphy, Nicholas, Ramakrishnan, Nithya, Vo-Le, Bylinda, Vo-Le, Brittany, Smith, Mark A., Iqbal, Tabish, Swann, Alan C., Mathew, Sanjay J., Lijffijt, Marijn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027791/ https://www.ncbi.nlm.nih.gov/pubmed/33318635 http://dx.doi.org/10.1038/s41386-020-00917-z |
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