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Establishing an immunocompromised porcine model of human cancer for novel therapy development with pancreatic adenocarcinoma and irreversible electroporation

New therapies to treat pancreatic cancer are direly needed. However, efficacious interventions lack a strong preclinical model that can recapitulate patients’ anatomy and physiology. Likewise, the availability of human primary malignant tissue for ex vivo studies is limited. These are significant li...

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Detalles Bibliográficos
Autores principales: Hendricks-Wenger, Alissa, Aycock, Kenneth N., Nagai-Singer, Margaret A., Coutermarsh-Ott, Sheryl, Lorenzo, Melvin F., Gannon, Jessica, Uh, Kyungjun, Farrell, Kayla, Beitel-White, Natalie, Brock, Rebecca M., Simon, Alexander, Morrison, Holly A., Tuohy, Joanne, Clark-Deener, Sherrie, Vlaisavljevich, Eli, Davalos, Rafael V., Lee, Kiho, Allen, Irving C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027815/
https://www.ncbi.nlm.nih.gov/pubmed/33828203
http://dx.doi.org/10.1038/s41598-021-87228-5