Structural variant evolution after telomere crisis

Telomere crisis contributes to cancer genome evolution, yet only a subset of cancers display breakage-fusion-bridge (BFB) cycles and chromothripsis, hallmarks of experimental telomere crisis identified in previous studies. We examine the spectrum of structural variants (SVs) instigated by natural te...

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Detalles Bibliográficos
Autores principales: Dewhurst, Sally M., Yao, Xiaotong, Rosiene, Joel, Tian, Huasong, Behr, Julie, Bosco, Nazario, Takai, Kaori K., de Lange, Titia, Imieliński, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027843/
https://www.ncbi.nlm.nih.gov/pubmed/33828097
http://dx.doi.org/10.1038/s41467-021-21933-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027843/
https://www.ncbi.nlm.nih.gov/pubmed/33828097
http://dx.doi.org/10.1038/s41467-021-21933-7

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