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Structural variant evolution after telomere crisis
Telomere crisis contributes to cancer genome evolution, yet only a subset of cancers display breakage-fusion-bridge (BFB) cycles and chromothripsis, hallmarks of experimental telomere crisis identified in previous studies. We examine the spectrum of structural variants (SVs) instigated by natural te...
Autores principales: | Dewhurst, Sally M., Yao, Xiaotong, Rosiene, Joel, Tian, Huasong, Behr, Julie, Bosco, Nazario, Takai, Kaori K., de Lange, Titia, Imieliński, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027843/ https://www.ncbi.nlm.nih.gov/pubmed/33828097 http://dx.doi.org/10.1038/s41467-021-21933-7 |
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