Mutation-specific non-canonical pathway of PTEN as a distinct therapeutic target for glioblastoma

PTEN is one of the most frequently altered tumor suppressor genes in malignant tumors. The dominant-negative effect of PTEN alteration suggests that the aberrant function of PTEN mutation might be more disastrous than deletion, the most frequent genomic event in glioblastoma (GBM). This study aimed...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Seung Won, Lee, Yeri, Shin, Kayoung, Koo, Harim, Kim, Donggeon, Sa, Jason K., Cho, Hee Jin, Shin, Hye-mi, Lee, Se Jeong, Kim, Hyunho, Chung, Seok, Shin, Jihye, Lee, Cheolju, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027895/
https://www.ncbi.nlm.nih.gov/pubmed/33828082
http://dx.doi.org/10.1038/s41419-021-03657-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027895/
https://www.ncbi.nlm.nih.gov/pubmed/33828082
http://dx.doi.org/10.1038/s41419-021-03657-0

Ejemplares similares