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Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models

[Image: see text] Quorum sensing is being investigated as an alternative therapeutic strategy in antibacterial drug discovery programs aimed at combatting bacterial resistance. LsrK is an autoinducer-2 kinase (belongs to the sugar kinase family), playing a key role in the phosphorylation of the auto...

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Detalles Bibliográficos
Autores principales: Medarametla, Prasanthi, Kronenberger, Thales, Laitinen, Tuomo, Poso, Antti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028047/
https://www.ncbi.nlm.nih.gov/pubmed/33683884
http://dx.doi.org/10.1021/acs.jcim.0c01233