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Polyanions Cause Protein Destabilization Similar to That in Live Cells

[Image: see text] The structural stability of proteins is found to markedly change upon their transfer to the crowded interior of live cells. For some proteins, the stability increases, while for others, it decreases, depending on both the sequence composition and the type of host cell. The mechanis...

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Detalles Bibliográficos
Autores principales: Sörensen, Therese, Leeb, Sarah, Danielsson, Jens, Oliveberg, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028048/
https://www.ncbi.nlm.nih.gov/pubmed/33635054
http://dx.doi.org/10.1021/acs.biochem.0c00889