Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies

Definitive diagnosis of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) relies on postmortem finding of disease-associated alpha-synuclein (αSyn(D)) as misfolded protein aggregates in the central nervous system (CNS). The recent development of the real-time quaking induced conversion (R...

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Detalles Bibliográficos
Autores principales: Bargar, Connor, Wang, Wen, Gunzler, Steven A., LeFevre, Alexandra, Wang, Zerui, Lerner, Alan J., Singh, Neena, Tatsuoka, Curtis, Appleby, Brian, Zhu, Xiongwei, Xu, Rong, Haroutunian, Vahram, Zou, Wen-Quan, Ma, Jiyan, Chen, Shu G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028088/
https://www.ncbi.nlm.nih.gov/pubmed/33827706
http://dx.doi.org/10.1186/s40478-021-01175-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028088/
https://www.ncbi.nlm.nih.gov/pubmed/33827706
http://dx.doi.org/10.1186/s40478-021-01175-w

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