Cargando…

Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies

Definitive diagnosis of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) relies on postmortem finding of disease-associated alpha-synuclein (αSyn(D)) as misfolded protein aggregates in the central nervous system (CNS). The recent development of the real-time quaking induced conversion (R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bargar, Connor, Wang, Wen, Gunzler, Steven A., LeFevre, Alexandra, Wang, Zerui, Lerner, Alan J., Singh, Neena, Tatsuoka, Curtis, Appleby, Brian, Zhu, Xiongwei, Xu, Rong, Haroutunian, Vahram, Zou, Wen-Quan, Ma, Jiyan, Chen, Shu G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028088/ https://www.ncbi.nlm.nih.gov/pubmed/33827706 http://dx.doi.org/10.1186/s40478-021-01175-w

Ejemplares similares

Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study
por: Kuzkina, Anastasia, et al.
Publicado: (2021)

Identification of α-Synuclein Proaggregator: Rapid Synthesis and Streamlining RT-QuIC Assays in Parkinson’s Disease
por: Takada, Fumito, et al.
Publicado: (2022)

Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies
por: Rossi, Marcello, et al.
Publicado: (2020)

α‐Synuclein RT‐QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies
por: Bongianni, Matilde, et al.
Publicado: (2019)

Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease
por: Hall, Sara, et al.
Publicado: (2022)

Correction to: Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies
por: Rossi, Marcello, et al.
Publicado: (2020)

RT‐QuIC Detection of Pathological α‐Synuclein in Skin Punches of Patients with Lewy Body Disease
por: Mammana, Angela, et al.
Publicado: (2021)

In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC
por: Donadio, Vincenzo, et al.
Publicado: (2021)

RT-QuIC: a new test for sporadic CJD
por: Green, Alison J E
Publicado: (2019)

Factors That Improve RT-QuIC Detection of Prion Seeding Activity
por: Orrú, Christina D., et al.
Publicado: (2016)

Alpha‐synuclein RT‐QuIC in the CSF of patients with alpha‐synucleinopathies
por: Fairfoul, Graham, et al.
Publicado: (2016)

Detection of CWD in cervids by RT-QuIC assay of third eyelids
por: Cooper, Sarah K., et al.
Publicado: (2019)

The Latest Research on RT-QuIC Assays—A Literature Review
por: Dong, Thi-Thu-Trang, et al.
Publicado: (2021)

Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories
por: Bargar, Connor, et al.
Publicado: (2021)

Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis
por: Peña-Bautista, Carmen, et al.
Publicado: (2023)

Preparation of lyophilized recombinant prion protein for TSE diagnosis by RT-QuIC
por: Hwang, Soyoun, et al.
Publicado: (2018)

RT-QuIC detection of tauopathies using full-length tau substrates
por: Tennant, Joanne M., et al.
Publicado: (2020)

Validation and Application of Skin RT-QuIC to Patients in China with Probable CJD
por: Xiao, Kang, et al.
Publicado: (2021)

Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease
por: Cramm, Maria, et al.
Publicado: (2015)

Extended and direct evaluation of RT‐QuIC assays for Creutzfeldt‐Jakob disease diagnosis
por: Groveman, Bradley R., et al.
Publicado: (2016)

Transmission of CJD from nasal brushings but not spinal fluid or RT‐QuIC product
por: Raymond, Gregory J., et al.
Publicado: (2020)

Hofmeister Effect in RT-QuIC Seeding Activity of Chronic Wasting Disease Prions
por: Hwang, Soyoun, et al.
Publicado: (2021)

Evaluation of sted super-resolution image quality by image correlation spectroscopy (QuICS)
por: Cerutti, Elena, et al.
Publicado: (2021)

Standardization of Data Analysis for RT-QuIC-Based Detection of Chronic Wasting Disease
por: Rowden, Gage R., et al.
Publicado: (2023)

α‐synuclein RT‐QuIC in cerebrospinal fluid of LRRK2‐linked Parkinson's disease
por: Garrido, Alicia, et al.
Publicado: (2019)

Second-Generation RT-QuIC Assay for the Diagnosis of Creutzfeldt-Jakob Disease Patients in Brazil
por: Barbosa, Breno José Alencar Pires, et al.
Publicado: (2020)

Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD
por: Orrú, Christina D., et al.
Publicado: (2020)

Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids
por: Bistaffa, Edoardo, et al.
Publicado: (2019)

Cross-validation of the RT-QuIC assay for the antemortem detection of chronic wasting disease in elk
por: Haley, N.J., et al.
Publicado: (2020)

ThermoMixer-Aided Endpoint Quaking-Induced Conversion (EP-QuIC) Permits Faster Sporadic Creutzfeldt-Jakob Disease (sCJD) Identification than Real-Time Quaking-Induced Conversion (RT-QuIC)
por: Vendramelli, Robert, et al.
Publicado: (2018)

RT-QuIC-based detection of alpha-synuclein seeding activity in brains of dementia with Lewy Body patients and of a transgenic mouse model of synucleinopathy
por: Han, Jung-Youn, et al.
Publicado: (2020)

Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid
por: Orrú, Christina D., et al.
Publicado: (2015)

Source genotype influence on cross species transmission of transmissible spongiform encephalopathies evaluated by RT-QuIC
por: Hwang, Soyoun, et al.
Publicado: (2018)

Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues
por: Luk, Collin C., et al.
Publicado: (2021)

RT-QuIC detection of CWD prion seeding activity in white-tailed deer muscle tissues
por: Li, Manci, et al.
Publicado: (2021)

RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein
por: Srivastava, Ankit, et al.
Publicado: (2022)

Salivary α‐Synuclein RT‐QuIC Correlates with Disease Severity in de novo Parkinson's Disease
por: Vivacqua, Giorgio, et al.
Publicado: (2022)

Prion Seeding Activities of Mouse Scrapie Strains with Divergent PrP(Sc) Protease Sensitivities and Amyloid Plaque Content Using RT-QuIC and eQuIC
por: Vascellari, Sarah, et al.
Publicado: (2012)

Epitope mapping of the protease resistant products of RT-QuIC does not allow the discrimination of sCJD subtypes
por: Piconi, Gabriele, et al.
Publicado: (2019)

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions
por: Franceschini, Alessia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_e28rc2781i77frfrfacm15nmsv