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SCF + G-CSF treatment in the chronic phase of severe TBI enhances axonal sprouting in the spinal cord and synaptic pruning in the hippocampus

Traumatic brain injury (TBI) is a major cause of long-term disability in young adults. An evidence-based treatment for TBI recovery, especially in the chronic phase, is not yet available. Using a severe TBI mouse model, we demonstrate that the neurorestorative efficacy of repeated treatments with st...

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Detalles Bibliográficos
Autores principales: Qiu, Xuecheng, Ping, Suning, Kyle, Michele, Chin, Lawrence, Zhao, Li-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028149/
https://www.ncbi.nlm.nih.gov/pubmed/33832542
http://dx.doi.org/10.1186/s40478-021-01160-3