Cargando…
SCF + G-CSF treatment in the chronic phase of severe TBI enhances axonal sprouting in the spinal cord and synaptic pruning in the hippocampus
Traumatic brain injury (TBI) is a major cause of long-term disability in young adults. An evidence-based treatment for TBI recovery, especially in the chronic phase, is not yet available. Using a severe TBI mouse model, we demonstrate that the neurorestorative efficacy of repeated treatments with st...
Autores principales: | Qiu, Xuecheng, Ping, Suning, Kyle, Michele, Chin, Lawrence, Zhao, Li-Ru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028149/ https://www.ncbi.nlm.nih.gov/pubmed/33832542 http://dx.doi.org/10.1186/s40478-021-01160-3 |
Ejemplares similares
-
Early life stress impairs synaptic pruning in the developing hippocampus
por: Dayananda, Kiran K., et al.
Publicado: (2023) -
Extrinsic inhibitors in axon sprouting and functional recovery after spinal cord injury
por: Meves, Jessica M., et al.
Publicado: (2014) -
Inosine Enhances Axon Sprouting and Motor Recovery after Spinal Cord Injury
por: Kim, Daniel, et al.
Publicado: (2013) -
CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability
por: Müller, Franziska, et al.
Publicado: (2022) -
Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABA(A) receptors on dendritic spines
por: Afroz, Sonia, et al.
Publicado: (2016)