Cargando…

Periostin loss-of-function protects mice from post-traumatic and age-related osteoarthritis

BACKGROUND: Elevated levels of periostin (Postn) in the cartilage and bone are associated with osteoarthritis (OA). However, it remains unknown whether Postn loss-of-function can delay or prevent the development of OA. In this study, we sought to better understand the role of Postn in OA development...

Descripción completa

Detalles Bibliográficos
Autores principales: Attur, Mukundan, Duan, Xin, Cai, Lei, Han, Tianzhen, Zhang, Weili, Tycksen, Eric D., Samuels, Jonathan, Brophy, Robert H., Abramson, Steven B., Rai, Muhammad Farooq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028178/
https://www.ncbi.nlm.nih.gov/pubmed/33832532
http://dx.doi.org/10.1186/s13075-021-02477-z