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Optimized permutation testing for information theoretic measures of multi-gene interactions

BACKGROUND: Permutation testing is often considered the “gold standard” for multi-test significance analysis, as it is an exact test requiring few assumptions about the distribution being computed. However, it can be computationally very expensive, particularly in its naive form in which the full an...

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Detalles Bibliográficos
Autores principales: Kunert-Graf, James M., Sakhanenko, Nikita A., Galas, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028212/
https://www.ncbi.nlm.nih.gov/pubmed/33827420
http://dx.doi.org/10.1186/s12859-021-04107-6