TGFβ pathway deregulation and abnormal phospho‐SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis‐Dutch type

Hereditary cerebral hemorrhage with amyloidosis‐Dutch type (HCHWA‐D) is an early onset hereditary form of cerebral amyloid angiopathy (CAA) pathology, caused by the E22Q mutation in the amyloid β (Aβ) peptide. Transforming growth factor β1 (TGFβ1) is a key player in vascular fibrosis and in the form...

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Detalles Bibliográficos
Autores principales: Grand Moursel, Laure, Munting, Leon P., van der Graaf, Linda M., van Duinen, Sjoerd G., Goumans, Marie‐Jose T. H., Ueberham, Uwe, Natté, Remco, van Buchem, Mark A., van Roon‐Mom, Willeke M. C., van der Weerd, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028662/
https://www.ncbi.nlm.nih.gov/pubmed/28557134
http://dx.doi.org/10.1111/bpa.12533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028662/
https://www.ncbi.nlm.nih.gov/pubmed/28557134
http://dx.doi.org/10.1111/bpa.12533

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