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Structure-based Design of a Specific, Homogeneous Luminescence Enzyme Reporter Assay for SARS-CoV-2

Recombinant antibodies (Abs) against the SARS-CoV-2 virus hold promise for treatment of COVID-19 and high sensitivity and specific diagnostic assays. Here, we report engineering principles and realization of a Protein-fragment Complementation Assay (PCA) detector of SARS-CoV-2 antigen by coupling tw...

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Detalles Bibliográficos
Autores principales:	Fellouse, Frederic A., Miersch, Shane, Chen, Chao, Michnick, Stephen W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028696/ https://www.ncbi.nlm.nih.gov/pubmed/33839165 http://dx.doi.org/10.1016/j.jmb.2021.166983

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