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Antitumor effect of IL-12 gene-modified bone marrow mesenchymal stem cells combined with Fuzheng Yiliu decoction in an in vivo glioma nude mouse model

BACKGROUND: Glioma is a complex cancer with a high morbidity and high mortality. Bone marrow mesenchymal stem cells (BMSCs) have shown promise as an excellent cell/drug delivery vehicle for gene-targeted therapy; however, maintaining genetic stability and biological activity remains difficult. Furth...

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Detalles Bibliográficos
Autores principales: Wu, Jianjun, Xie, Shoupin, Li, Hailong, Zhang, Yanxia, Yue, Jia, Yan, Chunlu, Liu, Kai, Liu, Yongqi, Xu, Rui, Zheng, Guisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028710/
https://www.ncbi.nlm.nih.gov/pubmed/33827606
http://dx.doi.org/10.1186/s12967-021-02809-2