Targeting neddylation E2s: a novel therapeutic strategy in cancer

Ubiquitin-conjugating enzyme E2 M (UBE2M) and ubiquitin-conjugating enzyme E2 F (UBE2F) are the two NEDD8-conjugating enzymes of the neddylation pathway that take part in posttranslational modification and change the activity of target proteins. The activity of E2 enzymes requires both a 26-residue...

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Detalles Bibliográficos
Autores principales: Zheng, Yi-Chao, Guo, Yan-Jia, Wang, Bo, Wang, Chong, Mamun, M. A. A., Gao, Ya, Liu, Hong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028724/
https://www.ncbi.nlm.nih.gov/pubmed/33827629
http://dx.doi.org/10.1186/s13045-021-01070-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028724/
https://www.ncbi.nlm.nih.gov/pubmed/33827629
http://dx.doi.org/10.1186/s13045-021-01070-w

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