A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis

BACKGROUND: Canine malignant melanoma is highly aggressive and generally chemoresistant. Toceranib is a kinase inhibitor drug that inhibits several tyrosine kinases including the proto-oncogene receptor tyrosine kinase KIT. Although canine malignant melanoma cells often express KIT, a therapeutic ef...

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Detalles Bibliográficos
Autores principales: Tani, Hiroyuki, Miyamoto, Ryo, Noguchi, Syunya, Kurita, Sena, Nagashima, Tomokazu, Michishita, Masaki, Yayoshi, Naoko, Tamura, Kyoichi, Bonkobara, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028755/
https://www.ncbi.nlm.nih.gov/pubmed/33827546
http://dx.doi.org/10.1186/s12917-021-02864-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028755/
https://www.ncbi.nlm.nih.gov/pubmed/33827546
http://dx.doi.org/10.1186/s12917-021-02864-3

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