Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells

C9ORF72 repeat expansion is the most frequent causal genetic mutation giving rise to amyotrophic lateral sclerosis (ALS) and fronto‐temporal dementia (FTD). The relatively recent discovery of the C9ORF72 repeat expansion in 2011 and the complexity of the mutation have meant that animal models that s...

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Detalles Bibliográficos
Autores principales: Selvaraj, Bhuvaneish T., Livesey, Matthew R., Chandran, Siddharthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
MINI‐SYMPOSIUM: USING iPSCs TO UNDERSTAND HUMAN NEUROLOGICAL DISEASE: POTENTIAL AND LIMITATIONS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029270/
https://www.ncbi.nlm.nih.gov/pubmed/28585384
http://dx.doi.org/10.1111/bpa.12520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029270/
https://www.ncbi.nlm.nih.gov/pubmed/28585384
http://dx.doi.org/10.1111/bpa.12520

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