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The mechanism by which imeglimin inhibits gluconeogenesis in rat liver cells

AIMS: To understand the mechanism by which imeglimin (a new oral hypoglycemic agent whose phase 3 development program in Japan has now been completed) decreases hepatic glucose production. MATERIALS AND METHODS: We compared the effect of imeglimin and metformin on glucose production, ATP/ADP ratio,...

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Detalles Bibliográficos
Autores principales: Vial, Guillaume, Lamarche, Frédéric, Cottet‐Rousselle, Cécile, Hallakou‐Bozec, Sophie, Borel, Anne‐Laure, Fontaine, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029524/
https://www.ncbi.nlm.nih.gov/pubmed/33855213
http://dx.doi.org/10.1002/edm2.211