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The cGAS–STING pathway as a therapeutic target in inflammatory diseases

The cGAS–STING signalling pathway has emerged as a key mediator of inflammation in the settings of infection, cellular stress and tissue damage. Underlying this broad involvement of the cGAS–STING pathway is its capacity to sense and regulate the cellular response towards microbial and host-derived...

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Detalles Bibliográficos
Autores principales: Decout, Alexiane, Katz, Jason D., Venkatraman, Shankar, Ablasser, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029610/
https://www.ncbi.nlm.nih.gov/pubmed/33833439
http://dx.doi.org/10.1038/s41577-021-00524-z