Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis

Individually, dysfunction of both the endoplasmic reticulum (ER) and mitochondria has been linked to aging, but how communication between these organelles might be targeted to promote longevity is unclear. Here, we provide evidence that, in Caenorhabditis elegans, inhibition of the conserved unfolde...

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Detalles Bibliográficos
Autores principales: Burkewitz, Kristopher, Feng, Gaomin, Dutta, Sneha, Kelley, Charlotte A., Steinbaugh, Michael, Cram, Erin J., Mair, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030272/
https://www.ncbi.nlm.nih.gov/pubmed/32905769
http://dx.doi.org/10.1016/j.celrep.2020.108125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030272/
https://www.ncbi.nlm.nih.gov/pubmed/32905769
http://dx.doi.org/10.1016/j.celrep.2020.108125

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